Moore,Wayne GR

Portrait photo of G R Wayne Moore

Dr.

Moore,Wayne GR

BSc (Nfld.), MD(McG.), FRCPC

Basic Info
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Academic Rank:

Clinical Professor, Dept of Pathology & Laboratory Medicine, Faculty of Medicine, University of British Columbia

Affiliation(s):

ICORD

Location:

Vancouver General Hospital

Short Bio

Sugar molecules attached to proteins expressed at the cell surface are increasingly recognized as playing an important role in the control of cell-cell interaction. Specific oligosaccharides can be recognized by sugar binding proteins (so called lectins) and this interaction has the potential to control how a cell interacts with other cells.  Dr. Ziltener is studying the enzymes, “glycosyltransferases” that allow formation of oligosaccharide groups made from sugars such as sialic acid, fucose, galactose and N-acetylglucosamine to form ligands for selectins. Expression of selectin ligands for instance on cells of the immune system is required for these cells to migrate to a site of inflammation, leave the blood vessel and migrate into the tissue where they then participate in the immune response to e.g. a pathogen. Understanding the mechanisms that control the activities of glycosyltransferases that lead to formation of selectin ligands will thus lead to a better understanding of processes that control migration of cells of the immune system to sites of inflammation.

Academic
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Academic Backgrounds

  • Fellow of the Royal College of Pathologists (UK). 2007
  • Certification in Neuropathology by the Royal College of Physicians and Surgeons of Canada. 1980
  • Certification in Neurology by the Royal College of Physicians and Surgeons of Canada. 1978
  • MD, CM, McGill University, Montreal, QC. 1972
  • BSc, Memorial University of Newfoundland, St. John’s, NL. 1968

Awards & Recognition


Selected Publications

Research
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Current Openings & Opportunities

Please contact Dr. Moore with inquiries.


Current Projects In My Lab include


Research

  • Multiple Sclerosis
  • spinal cord injury

Dr. Moore conducts research on the pathology of multiple sclerosis (MS) and spinal cord injury. Dr. Moore is a Principal Investigator at ICORD and a Clinical Professor in the Department of Pathology and Laboratory Medicine at the University of British Columbia. He completed his B.Sc. at Memorial University of Newfoundland, and his M.D. at McGill University.

Teaching
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Teaching